| Head east on Via Delle due Sicilie | 40 m |
| Turn right onto Via Giuseppe Mazzini | 150 m |
| Turn left onto Via Rocco Pirri | 200 m |
| Turn left onto Via Fra' Serafino Mannone | 150 m |
| Continue onto Piazza Giacomo Matteotti | 250 m |
| Continue onto Viale Roma | 550 m |
| Continue onto Via Giovanni Gentile | 1.5 km |
| Continue onto Strada statale di Gibellina (SS119) | 6 km |
| Take the ramp on the right towards A29: Mazara del Vallo | 200 m |
| Keep left towards A29: Palermo | 700 m |
| Merge left onto Autostrada Palermo-Mazara del Vallo (A29) | 80 km |
| Continue onto Raccordo per Via Belgio (A29racc/bis) | 5.5 km |
| Continue onto Viale Regione Siciliana Nord Ovest | 5.5 km |
| Continue onto Viale Regione Siciliana Sud Est | 5.5 km |
| Continue towards Catania | 5.5 km |
| Continue onto Autostrada Palermo-Catania (A19) | 40 km |
| Take the ramp on the left towards A20: Messina | 450 m |
| Continue towards Messina | 1 km |
| Continue onto Autostrada Messina-Palermo (A20) | 900 m |
| Take the ramp on the left | 300 m |
| Merge right onto Autostrada Messina-Palermo (A20) | 25 km |
| Continue onto Galleria Sant'Ambrogio (A20) | 2 km |
| Continue onto Viadotto Malpertugio (A20) | 700 m |
| Continue onto Autostrada Messina-Palermo (A20) | 10 km |
| Continue onto Viadotto Buongiorno (A20) | 350 m |
| Continue onto Autostrada Messina-Palermo (A20) | 9 km |
| Continue onto Galleria Colonna (A20) | 1 km |
| Continue onto Viadotto Serravalle (A20) | 450 m |
| Continue onto Autostrada Messina-Palermo (A20) | 5 km |
| Continue onto Viadotto Ledera (A20) | 300 m |
| Continue onto Galleria Portale (A20) | 700 m |
| Continue onto Viadotto Portale (A20) | 450 m |
| Continue onto Galleria Pagliarotto (A20) | 900 m |
| Continue onto Autostrada Messina-Palermo (A20) | 150 m |
| Continue onto Viadotto Caronia (A20) | 600 m |
| Continue onto Galleria Caronia (A20) | 2 km |
| Continue onto Autostrada Messina-Palermo (A20) | 15 km |
| Continue onto Viadotto Inganno (A20) | 400 m |
| Continue onto Galleria Inganno (A20) | 350 m |
| Continue onto Autostrada Messina-Palermo (A20) | 2.5 km |
| Continue onto Viadotto Posta (A20) | 250 m |
| Continue onto Galleria San Bartolomeo (A20) | 500 m |
| Continue onto Autostrada Messina-Palermo (A20) | 10 km |
| Continue onto Viadotto Forno (A20) | 350 m |
| Continue onto Galleria Capo d'Orlando (A20) | 2 km |
| Continue onto Autostrada Messina-Palermo (A20) | 1 km |
| Continue onto Viadotto Buongiorno (A20) | 100 m |
| Continue onto Galleria San Cono (A20) | 1.5 km |
| Continue onto Viadotto Santa Carrà (A20) | 150 m |
| Continue onto Galleria Baldassarre (A20) | 900 m |
| Continue onto Viadotto Naso (A20) | 500 m |
| Continue onto Galleria Cipolla (A20) | 1.5 km |
| Continue onto Viadotto Brolo (A20) | 150 m |
| Continue onto Autostrada Messina-Palermo (A20) | 55 km |
| Continue onto Galleria Sant'Antonio (A20) | 450 m |
| Continue onto Galleria Grangiara (A20) | 350 m |
| Continue onto Autostrada Messina-Palermo (A20) | 1 km |
| Continue onto Galleria Malerba (A20) | 300 m |
| Continue onto Viadotto Tonnarazza (A20) | 200 m |
| Continue onto Autostrada Messina-Palermo (A20) | 350 m |
| Continue onto Viadotto Pietra (A20) | 200 m |
| Continue onto Galleria Buonsignore (A20) | 300 m |
| Continue onto Viadotto Formica (A20) | 100 m |
| Continue onto Autostrada Messina-Palermo (A20) | 15 km |
| Continue onto Galleria Baglio (A20) | 400 m |
| Take the ramp | 900 m |
| Continue onto Svincolo Messina Giostra | 600 m |
| Keep left at the fork | 25 m |
| Enter the traffic circle and take the 1st exit onto Viale Giostra | 3.5 m |
| Exit the traffic circle onto Viale Giostra | 400 m |
| Enter the traffic circle and take the 2nd exit onto Viale Giostra | 25 m |
| Exit the traffic circle onto Viale Giostra | 600 m |
| Enter the traffic circle and take the 3rd exit | 40 m |
| Exit the traffic circle | 10 m |
| Continue onto Viale Giostra | 900 m |
| Enter the traffic circle and take the 2nd exit onto Viale Giostra | 80 m |
| Exit the traffic circle onto Viale Giostra | 1 km |
| Continue straight | 200 m |
| Turn left | 350 m |
| Keep left at the fork | 90 m |
| Keep right at the fork | 150 m |
| Take the ferry Messina - Villa San Giovanni | 7 km |
| Continue straight | 20 m |
| Turn right | 200 m |
| Go straight onto Via dei Marinai d'Italia | 350 m |
| Turn right | 550 m |
| Continue straight | 200 m |
| Go straight onto Strada Statale 738 di Villa San Giovanni (SS738) | 900 m |
| Take the ramp | 60 m |
| Keep left towards A2: Salerno | 700 m |
| Merge left onto Autostrada del Mediterraneo (A2) | 150 km |
| Continue onto Viadotto Caselle (A2) | 350 m |
| Continue onto Galleria San Lorenzo (A2) | 150 m |
| Continue onto Viadotto Profenna (A2) | 350 m |
| Continue onto Autostrada del Mediterraneo (A2) | 300 m |
| Continue onto Viadotto San Martino (A2) | 600 m |
| Continue onto Viadotto Specola (A2) | 400 m |
| Continue onto Viadotto Torre Trocini (A2) | 600 m |
| Continue onto Autostrada Viadotto Molino Irto (A2) | 600 m |
| Continue onto Acqua di Calci (A2) | 350 m |
| Continue onto Autostrada del Mediterraneo (A2) | 50 km |
| Take the ramp | 700 m |
| Make a slight left | 500 m |
| Merge left onto Strada Statale 534 di Cammarata e degli Stombi (SS534) | 20 km |
| Keep right at the fork | 450 m |
| Enter the traffic circle and take the 3rd exit onto SP253 | 45 m |
| Exit the traffic circle onto SP253 | 2.5 km |
| Continue onto SP169 | 800 m |
| Enter the traffic circle and take the 2nd exit onto Viale della Magna Grecia | 15 m |
| Exit the traffic circle onto Viale della Magna Grecia | 350 m |
| Continue onto Strada Provinciale 253 (SP253) | 1.5 km |
| Take the ramp on the left | 200 m |
| Merge left onto Strada Statale 106 Jonica (SS106) | 30 km |
| Continue onto DEVIAZIONE SS106 Jonica (SS106) | 1.5 km |
| Continue onto Strada Statale 106 Jonica (SS106) | 50 km |
| Keep left onto Strada Statale 106 Jonica (SS106) | 25 km |
| Take the ramp onto SS106 | 500 m |
| Enter the traffic circle and take the 4th exit onto Strada Statale 106 Ionica diramazione (SS106dir) | 150 m |
| Exit the traffic circle onto Strada Statale 106 Ionica diramazione (SS106dir) | 350 m |
| Continue onto SS106dir | 1 km |
| Continue onto Strada Statale 106 Ionica diramazione (SS106dir) | 6 km |
| Continue onto Strada Statale 7 Appia (SS7) | 2 km |
| Continue straight to stay on Strada Statale 7 Appia (SS7) | 700 m |
| Merge left onto Strada Statale 7 Via Appia (SS7) | 150 m |
| Take the ramp onto Autostrada Adriatica (A14) | 500 m |
| Merge left onto Autostrada Adriatica (A14) | 800 km |
| Take the ramp towards MODENA sud | 1 km |
| Enter the traffic circle and take the 1st exit onto Strada Vignolese (SS623) | 20 m |
| Exit the traffic circle onto Strada Vignolese (SS623) | 1.5 km |
| Enter the traffic circle and take the 2nd exit onto Strada Vignolese (SS623) | 40 m |
| Exit the traffic circle onto Strada Vignolese (SS623) | 5 km |
| Enter the traffic circle and take the 2nd exit onto Strada Vignolese | 90 m |
| Exit the traffic circle onto Strada Vignolese | 1.5 km |
| Continue slightly right onto Via Marzabotto | 350 m |
| Turn left onto Viale Gaetano Moreali | 250 m |
| Turn left onto Via Domenico Cucchiari | 350 m |
| Continue onto Viale Piero Gobetti | 250 m |
| Enter Piazza Alessandro Manzoni and take the 1st exit onto Viale Medaglie D'Oro | 25 m |
| Exit the traffic circle onto Viale Medaglie D'Oro | 300 m |
| Enter the traffic circle and take the 3rd exit onto Via Carlo Sigonio | 30 m |
| Exit the traffic circle onto Via Carlo Sigonio | 900 m |
| Continue slightly right onto Via Pietro Giannone | 200 m |
| Continue onto Corso Canalchiaro | 500 m |
| You have arrived at your destination, straight ahead | 0 m |